CyTOF in the Cancer Immune Monitoring and Analysis Centers (CIMAC): Standardization & Harmonization

In 2017, the NCI established four Cancer Immune Monitoring and Analysis Centers (CIMACs), which perform standardized, state-of-the-art immunological assays for selected cancer immunotherapy clinical trials. One such assay is CyTOF® immunophenotyping, for which the four CIMAC centers performed cross-site harmonization.

In this presentation, Maecker describes the results and lessons learned from those harmonization efforts, as well as plans for using the Maxpar® Direct™ Immune Profiling Assay™, a standardized, dry-format, high-parameter immunophenotyping assay for mass cytometry, in future CIMAC studies.

This presentation was recorded during the 2021 Fluidigm Mass Cytometry Summit, Igniting Insight into Human Health: The CyTOF Edge.

ABOUT THE SPEAKER:
Holden Maecker, PhD
Professor of Microbiology and Immunology
Director of the Human Immune Monitoring Center
Stanford University

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